CRI Genetics Blog

The Science of Sipping: How Your Genes Affect Red Wine’s Benefits

Written by Grace Magalit | Feb 13, 2025 11:57:42 PM

If you’ve watched Scandal, you’ve probably noticed that Olivia Pope always has a glass in hand. But let’s be real. She’s not drinking it for its heart-health benefits. More likely, it’s her way of unwinding after tackling political scandals and fixing White House crises.   
 
But here’s the twist… Olivia’s love for red wine might actually be doing more for her than she realizes. So, in true Scandal fashion, let’s break it down, investigate the science, and uncover the real benefits of red wine… just like Olivia would in one of her high-stakes cases. 🍷  

What exactly is red wine? 

Red wine is a popular alcoholic beverage made from fermented dark-colored grapes. Its deep red hue comes from the grape skins, which remain in contact with the juice during fermentation, unlike white wine, where the skins are removed early. This process not only gives red wine its rich flavor but also enhances its levels of tannins, antioxidants like resveratrol, and polyphenols, which are compounds linked to potential health benefits.  

Because of these natural compounds, red wine has long been associated with heart health and longevity, making it a drink enjoyed for both its taste and its possible wellness perks.  

And when it comes to health, here are the main benefits of drinking red wine.  

However, not everyone gets the same level of benefits from drinking red wine. Some people are lucky enough to need just a small amount to maximize its health perks, while others may need to drink more to experience its full potential. Maybe that’s why Olivia Pope always has a glass in hand… she might just be one of those people who need a little extra to reap the health benefits.

So, what can help your body maximize red wine’s health benefits?  

Meet your COMT gene. This gene helps your body break down certain compounds, including dopamine (a brain chemical that affects mood) and polyphenols (healthy plant compounds found in red wine). One of its key jobs is breaking down resveratrol and flavonoids, which are antioxidants that help protect your heart and reduce inflammation. So, how well your body processes these beneficial compounds may depend on your COMT gene! 

A small genetic change in your COMT gene, specifically a variation in a SNP (single nucleotide polymorphism), can affect how well this enzyme works. This change plays a role in how efficiently your body breaks down and processes beneficial compounds in red wine, like resveratrol and flavonoids. As a result, it can influence how much cardiovascular and brain-boosting benefits you get from drinking red wine in moderation! 

But why does this matter?   

Understanding your DNA through DNA testing and knowing how your body processes the health benefits of red wine can help you make smarter choices. If your genes allow you to absorb more of red wine’s antioxidants, a small amount might be enough. But if your body processes these compounds differently, you might need a bit more to maximize the benefits. Either way, moderation is key! Too much red wine can have health risks, so knowing your genetic response helps you enjoy it wisely. 

And since it’s Valentine’s season, chances are you’ll be raising a glass of red wine at some point! As you enjoy its rich aroma and smooth taste, take a moment to thank your genes for how they process its health benefits. Whether you only need one glass or a bit more to maximize its perks, knowing your body’s unique response can help you sip smarter and healthier.

Here’s a Red Wine fun fact  

Did you know that red wine has been around for over 8,000 years? The earliest evidence of winemaking was discovered in the South Caucasus region (modern-day Georgia), where people accidentally learned that fermented grapes turned into wine. Archaeologists have even found ancient clay jars containing traces of red wine, with some decorated with grape clusters and dancing figures.  

Curious about which variant you have and how it influences your body's response to this popular drink? Read our Health Benefits of Red Wine health report and learn more about how red wine is made and its potential health benefits, and even step into the shoes of your favorite TV and movie characters who love a good glass of red. Cheers to science and wine! 

Make smarter lifestyle decisions by learning more about your DNA! 

And it’s not just about red wine. Your DNA plays a role in many aspects of your health and daily life. From seasonal hay allergies, seafood sensitivities, and menopause timing, to your ability to smell floral scents, your genes shape how your body reacts to the world around you. Even something as simple as choosing the right cooking oil (you may need to switch to olive oil) can be influenced by your genetic makeup.  

By understanding your DNA, you can make smarter choices about what you eat and drink, helping you live a healthier, more comfortable, and stress-free life! 🧬✨ So, what are you waiting for? The more you know about your genetic makeup, the better you can optimize your lifestyle. 

At CRI Genetics, we’re committed to helping you unlock the secrets of your DNA. Through advanced DNA testing, we provide insights into your unique traits, from food sensitivities to how your body processes nutrients, and even some of your personality traits (like attachment style), so you can make choices that truly work for you!

 

 

 

 

References:  
https://www.bbc.com/news/world-europe-41977709  
https://www.healthline.com/nutrition/red-wine-good-or-bad  
https://www.refinery29.com/en-us/2017/05/154218/scandal-wine-what-it-really-is